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User:Cy9911/ISET检测

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ISET Test
A circulating tumor cell (arrow) diagnosed by the ISET test. (The pores of the filter are also visible.)
作用Detect tumor cells
測試Blood

ISET检测（英語：Isolation by Size of Epithelial Tumor cells）是一种通过分离血液样本中的循环肿瘤细胞来早期发现癌症的医学检测。该测试采用了由法国国家健康与医学研究院、巴黎笛卡尔大学和巴黎公共医院开发的流程，旨在分离样本中存在的所有循环癌细胞并使用细胞病理学方法识别它们。

癌细胞和非癌细胞一样在血液中循环。肿瘤细胞用箭头标记 ；根据Hofman et al. ,, 2011 (8) A, b, c :肿瘤细胞， d, e, f :非典型细胞， g, h, i :正常细胞。

參考資料

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  • Krebs, M.; et al. Analysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent Approaches. Journal of Thoracic Oncology. février 2012, 7 (2): 306–315. doi:10.1097/jto.0b013e31823c5c16. 
  • Farace, F.; et al. A Direct Comparison of CellSearch™ and ISET® for Circulating Tumour-Cell Detection in Patients with Metastatic Carcinomas. British Journal of Cancer. septembre 2011, 105 (6): 847–853. doi:10.1038/bjc.2011.294. 
  • Khoja, L.; et al. A pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker. British Journal of Cancer. 31 janvier 2012, 106 (3): 508–516. doi:10.1038/bjc.2011.545. 
  • Khoja, L.; et al. Prevalence and heterogeneity of circulating tumour cells in metastatic cutaneous melanoma. Melanoma Research. février 2013, 24: 40–46. doi:10.1097/cmr.0000000000000025.  已忽略未知参数|numéro= (帮助);
  • Hofman, V.; et al. Detection of circulating tumor cells as a prognostic factor in patients undergoing radical surgery for non-small cell lung carcinoma: Comparison of the efficacy of the CellSearch Assay™ and the isolation by size of epithelial tumor cell method®. International Journal of Cancer. 1 octobre 2011, 129: 1651–1660. doi:10.1002/ijc.25819.  已忽略未知参数|numéro= (帮助);
  • Pailler, E.; et al. Detection of circulating tumor cells harboring a unique ALK rearrangement in ALK-positive non–small-cell lung cancer. Journal of Clinical Oncology. 20 juin 2013, 31: 2273–2281. doi:10.1200/jco.2012.44.5932.  已忽略未知参数|numéro= (帮助);
  • Vona, G.; et al. ISET, Isolation by Size of Epithelial Tumor cells: a new method for isolation, immunomorphological and molecular characterization of circulating tumor cells. American Journal of Pathology. janvier 2000, 156: 57–63.  已忽略未知参数|numéro= (帮助);
  • Hofman, V. Cytopathologic Detection of Circulating Tumor Cells Using the Isolation by Size of Epithelial Tumor Cell Method. American Journal of Clinical Pathology. janvier 2011, 135: 146–156. doi:10.1309/ajcp9x8ozbeiqvvi.  已忽略未知参数|numéro= (帮助); 已忽略未知参数|et al.= (帮助);
  • Ilie. “Sentinel” Circulating Tumor Cells Allow Early Diagnosis of Lung Cancer in Patients with Chronic Obstructive Pulmonary Disease (PDF). Plos One: 9(10): e111597. doi:10.1371/journal.pone.0111597. Octobre 2014.  已忽略未知参数|et al.= (帮助);
  • Laget. Technical Insights into Highly Sensitive Isolation and Molecular Characterization of Fixed and Live Circulating Tumor Cells for Early Detection of Tumor Invasion (PDF). Plos One: 12(1): e0169427. doi:10.137 1/journal.pone .0169427. Janvier 2017.  已忽略未知参数|et al.= (帮助);

外部連結

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