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TATA結合蛋白

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維基百科，自由的百科全書
TATA結合蛋白
已知的結構
PDB直系同源搜尋: PDBe RCSB
識別號
別名TBP；, GTF2D, GTF2D1, HDL4, SCA17, TFIID, TATA-box binding protein, TATA-binding protein, TBP1
外部IDOMIM：600075 MGI：101838 HomoloGene：2404 GeneCards：TBP
相關疾病
spinocerebellar ataxia type 17[1]
基因位置（人類）
6號染色體
染色體6號染色體[2]
6號染色體
TATA結合蛋白的基因位置
TATA結合蛋白的基因位置
基因座6q27起始170,554,302 bp[2]
終止170,572,870 bp[2]
RNA表達模式
查閱更多表達數據
直系同源
物種人類小鼠
Entrez

6908

21374

Ensembl

ENSG00000112592

ENSMUSG00000014767

UniProt

P20226

P29037

mRNA​序列

NM_003194
​NM_001172085

NM_013684

蛋白序列

NP_001165556
​NP_003185

NP_038712

基因位置​（UCSC）Chr 6: 170.55 – 170.57 MbChr 17: 15.72 – 15.75 Mb
PubMed​查找[4][5]
維基數據
檢視/編輯人類檢視/編輯小鼠
TBP
crystal structure of a yeast brf1-tbp-dna ternary complex
鑑定
標誌TBP
PfamPF00352（舊版）
Pfam宗系CL0407（舊版）
InterPro（英語：InterPro）IPR000814
PROSITE（英語：PROSITE）PDOC00303
SCOP（英語：Structural Classification of Proteins）1tbp / SUPFAM

TATA結合蛋白質（英語：TATA-binding protein，TBP）是一種通用轉錄因子，具體結合於DNA序列上的TATA盒。TATA盒位於真核基因的轉錄起始位點上游約25個bp，屬於啟動子區[6]。TBP可以和各個TBP相關因子共同組成通用轉錄因子TFIID,再進一步組成RNA聚合酶Ⅱ的轉錄起始複合物[7]。

蛋白質的相互作用

[編輯]

TATA結合蛋白與下列蛋白質進行互作：

參考文獻

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外部連結

[編輯]
取自 "https://zh.wikipedia.org/w/index.php?title=TATA结合蛋白&oldid=76075663"