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3-甲基苯环己哌啶

维基百科,自由的百科全书
3'-Me-PCP
法律规范状态
法律规范
识别信息
  • 1-[1-(3-methylphenyl)cyclohexyl]piperidine
CAS号2201-30-1  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C18H27N
摩尔质量257.42 g·mol−1
3D模型(JSmol英语JSmol
  • CC1=CC(=CC=C1)C2(CCCCC2)N3CCCCC3
  • InChI=1S/C18H27N/c1-16-9-8-10-17(15-16)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h8-10,15H,2-7,11-14H2,1H3
  • Key:BMFKUCGCXMDGBK-UHFFFAOYSA-N

3-甲基苯环己哌啶(英语:3-Methyl-PCP或3'-Methyl-PCP、meta-Methyl-PCP、3-Me-PCP)是一种含氮有机化合物,分子式C18H27N,属于苯环己哌啶(PCP)类的芳基环己胺,与3-甲氧基苯环己哌啶结构相似[1][2],用作解离剂狡诈家药物,1960年代首次合成[3]

参考文献

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  1. ^ Linders J, Furlano DC, Mattson MV, Jacobson AE, Rice KC. Synthesis and preliminary biochemical evaluation of novel derivatives of PCP.. Letters in Drug Design & Discovery. February 2010, 7 (2): 79–87. doi:10.2174/157018010790225813. 
  2. ^ Wallach J, De Paoli G, Adejare A, Brandt SD. Preparation and analytical characterization of 1-(1-phenylcyclohexyl)piperidine (PCP) and 1-(1-phenylcyclohexyl)pyrrolidine (PCPy) analogues. Drug Testing and Analysis. 2014, 6 (7–8): 633–50. PMID 23554350. doi:10.1002/dta.1468. 
  3. ^ Maddox VH, Godefroi EF, Parcell RF. The synthesis of phencyclidine and other 1-arylcyclohexylamines.. Journal of Medicinal Chemistry. March 1965, 8 (2): 230–5. PMID 14332667. doi:10.1021/jm00326a019. 

外部链接

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