JWH-147

JWH-147
法律規範狀態
法律規範	英：Class B; 美：附表I; Illegal in Sweden;
識別資訊
	IUPAC命名法 (1-Hexyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenyl-methanone; ;
CAS號	914458-20-1
ChemSpider	23277882 ;
UNII	MQ6N4B8QWE;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID00658823 ;
化學資訊
化學式	C27H27NO
摩爾質量	381.52 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES c4ccccc4-c2cc(cn2CCCCCC)C(=O)c1cccc3c1cccc3;
	InChI InChI=1S/C27H27NO/c1-2-3-4-10-18-28-20-23(19-26(28)22-13-6-5-7-14-22)27(29)25-17-11-15-21-12-8-9-16-24(21)25/h5-9,11-17,19-20H,2-4,10,18H2,1H3 ; Key:FRMYAMAGHYHNKF-UHFFFAOYSA-N ;

JWH-147，化學名N-正己基-5-苯基-3-(1-萘甲酰基)吡咯，分子式C
27H
27NO，屬於萘甲酰基吡咯類JWH系列大麻素，是大麻素受體CB₁和CB₂的激動劑^[1]。它可通過LC-MS法檢測，其前體離子的m/z為382，產物離子的m/z為127。^[2]

參考文獻

^ Huffman JW, Padgett LW, Isherwood ML, Wiley JL, Martin BR. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB₁ and CB₂ receptors. Bioorganic & Medicinal Chemistry Letters. October 2006, 16 (20): 5432–5. PMID 16889960. doi:10.1016/j.bmcl.2006.07.051.
^ Arianna Giorgetti; et al. Development and validation of a rapid LC-MS/MS method for the detection of 182 novel psychoactive substances in whole blood. Drug Testing and Analysis (2022), 14 (2), 202-223. doi:10.1002/dta.3170.