睾酮17β-脫氫酶 (NADP+)
| 睾酮17β-脫氫酶 (NADP+) | |||||||||
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| 識別碼 | |||||||||
| EC編號 | 1.1.1.64 | ||||||||
| CAS號 | 9028-63-1 | ||||||||
| 數據庫 | |||||||||
| IntEnz | IntEnz瀏覽 | ||||||||
| BRENDA | BRENDA入口 | ||||||||
| ExPASy | NiceZyme瀏覽 | ||||||||
| KEGG | KEGG入口 | ||||||||
| MetaCyc | 代謝路徑 | ||||||||
| PRIAM | 概述 | ||||||||
| PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
| 基因本體 | AmiGO / EGO | ||||||||
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睾酮17β-脫氫酶 (NADP+)（英語：testosterone 17β-dehydrogenase (NADP+)，EC 1.1.1.64 （頁面存檔備份，存於互聯網檔案館））是一種以NAD+或NADP+為受體、作用於供體CH-OH基團上的氧化還原酶。這種酶能催化以下酶促反應：
睾酮17β-脫氫酶 (NADP+)主要參與雄激素和雌激素代謝過程。
參考文獻
[編輯]- ENDAHL GL, KOCHAKIAN CD, HAMM D. Separation of a triphosphopyridine nucleotide-specific from a diphosphopyridine nucleotide-specific 17 beta-hydroxy-(testosterone) dehydrogenase of guinea pig liver. J. Biol. Chem. 1960, 235: 2792–6. PMID 13696735.
- SWEAT ML, SAMUELS LT, LUMRY R. Preparation and characterization of the enzyme which converts testosterone to androstenedione. J. Biol. Chem. 1950, 185 (1): 75–84. PMID 15436478.
- Villee CA and Spencer JM. Some properties of the pyridine nucleotide-specific 17beta-hydroxy steroid dehydrogenase of guinea pig liver. J. Biol. Chem. 1960, 235: 3615–3619. PMID 13781425.