RNA聚合酶V
RNA聚合酶V（英語：RNA polymerase V）是一種植物細胞核中特有的RNA聚合酶，和RNA聚合酶IV一樣參與小干擾RNA(siRNA)的轉錄。RNA聚合酶V轉錄siRNA誘導DNA甲基化而導致異染色質沉默。[1]
RNA聚合酶V由12個亞基組成，與RNA聚合酶Ⅱ亞基旁系同源。兩個最大的亞基（催化位置）是最保守的，與真核生物和細菌的聚合酶都有很高的相似性。[2]
參考文獻
[編輯]- ^ Wierzbicki, A; Haag, J; Pikaard, CS. Noncoding transcription by RNA Polymerase Pol IVb/Pol V mediates transcriptional silencing of overlapping and adjacent genes. Cell. 2008, 135: 635–648. PMC 2602798
. PMID 19013275. doi:10.1016/j.cell.2008.09.035.
- ^ Ream, TS; Haag, JR; Wierzbicki, AT; Nicora, CD; Norbeck, AD; Zhu, JK; Hagen, G; Guilfoyle, TJ; Pasa-Tolić, L; Pikaard, CS. Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II. Mol Cell: 192–203. PMC 2946823 . PMID 19110459. doi:10.1016/j.molcel.2008.12.015.
