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帽柱木鹼

維基百科,自由的百科全書
Mitragynine
臨床資料
給藥途徑口服給藥
藥物類別英語Drug class鴉片
ATC碼
  • 未分配
法律規範狀態
法律規範
  • 受管控(S8)
  • 未列入管制
  • NpSG
  • 未列入管制
  • PSA
  • 未列入管制
  • UN未列入管制
  • In general legal for medical and research uses as a research chemical.[1]
藥物動力學數據
生物利用度21%
代謝產物7-羥基帽柱鹼
生物半衰期7–39 hours
識別資訊
  • methyl (16E)-9,17-dimethoxy-16,17-didehydro-20β-corynan-16-carboxylate
CAS號4098-40-2
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C23H30N2O4
摩爾質量398.50 g·mol−1
3D模型(JSmol英語JSmol
熔點102–106 °C[3]
  • COC1=CC=CC2=C1C3=C([C@@](C[C@H](/C(C(OC)=O)=C\OC)[C@H](CC)C4)([H])N4CC3)N2
  • InChI=1S/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1
  • Key:LELBFTMXCIIKKX-QVRQZEMUSA-N

帽柱木鹼(英語:Mitragynine)是一種有機化合物,分子式C23H30N2O4,屬於吲哚生物鹼,存在於卡痛樹Mitragyna speciosa)等植物中,用作精神藥物[4]

參考文獻

[編輯]
  1. ^ 指定薬物一覧 [List of designated drugs] (PDF). 障害福祉のお仕事の世界 (The world of disability welfare work). [5 December 2023] (Japanese). 
  2. ^ Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-03-31 (2023-04-04) [2023-08-15]. (原始內容存檔於2023-08-03) (巴西葡萄牙語). 
  3. ^ Kratom profile (chemistry, effects, other names, origin, mode of use, other names, medical use, control status). European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). 
  4. ^ Hassan Z, Muzaimi M, Navaratnam V, Yusoff NH, Suhaimi FW, Vadivelu R, Vicknasingam BK, Amato D, von Hörsten S, Ismail NI, Jayabalan N, Hazim AI, Mansor SM, Müller CP. From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction. Neuroscience and Biobehavioral Reviews. February 2013, 37 (2): 138–151. PMID 23206666. S2CID 8463133. doi:10.1016/j.neubiorev.2012.11.012.