ASP2535

ASP2535
	IUPAC名; 4-[3-(6-phenylpyridin-3-yl)-5-propan-2-yl-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole
識別
CAS號	374886-51-8
PubChem	9800113
SMILES	CC(C)C1=NN=C(N1C2=CC=CC3=NON=C32)C4=CN=C(C=C4)C5=CC=CC=C5;
性質
化學式	C22H18N6O
摩爾質量	382.42 g·mol−1
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

它可以6-苯基煙酸，4-氨基苯並呋咱和2-甲基丙酰肼為原料經多步反應製得。^[2]

參考文獻

^ Harada, Katsuya; Nakato, Kazuhiro; Yarimizu, Junko; Yamazaki, Mayako; Morita, Masahiko; Takahashi, Shinji; Aota, Masaki; Saita, Kyoko; Doihara, Hitoshi; Sato, Yuichiro; Yamaji, Takayuki; Ni, Keni; Matsuoka, Nobuya. A novel glycine transporter-1 (GlyT1) inhibitor, ASP2535 (4-[3-isopropyl-5-(6-phenyl-3-pyridyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole), improves cognition in animal models of cognitive impairment in schizophrenia and Alzheimer's disease. European Journal of Pharmacology. 2012-06-15, 685 (1–3): 59–69. ISSN 1879-0712. PMID 22542656. doi:10.1016/j.ejphar.2012.04.013.
^ Sano, Kuniyuki; Sakaida, Uro. Process for preparation of benzoxadiazole compound. 2009. JP2009280554.

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