鐵屎米-6-酮

鐵屎米-6-酮
英文名	Canthin-6-one
別名	6-鐵屎米酮
識別
CAS號	479-43-6
SMILES	O=C1C=CC2=NC=CC=3C4=CC=CC=C4N1C23;
性質
化學式	C14H8N2O
摩爾質量	220.23 g·mol−1
外觀	白色晶體
熔點	161~163 °C
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

鐵屎米-6-酮（6H-吲哚並[3,2,1-de][1,5]萘啶-6-酮）是一種有機化合物，化學式為C₁₄H₈N₂O。它可由8-(2-氯苯基)-1,5-萘啶-2-酮和碳酸銫在N,N'-二甲基乙二胺和碘化亞銅的催化下反應製得。^[2]它在鈀催化下加氫，可以得到4,5-二氫鐵屎米-6-酮；它也可以被mCPBA氧化為鐵屎米-6-酮-N-氧化物。^[1]

參考文獻

^ ^1.0 ^1.1 ^1.2 Gerardo Cebrián-Torrejón, Nicolas Mackiewicz, Rafael P. Vázquez-Manrique, Alain Fournet, Bruno Figadère, Julien Nicolas, Erwan Poupon. Solution Phase and Nanoparticular Biosynthetically Inspired Interconnections in the Canthin-6-one β-Carboline Series and Study of Phenotypic Properties on C. elegans. European Journal of Organic Chemistry. 2013. 26. 5821-5828. doi:10.1002/ejoc.201300770.
^ Gollner, Andreas; Koutentis, Panayiotis A. Two-Step Total Syntheses of Canthin-6-one Alkaloids: New One-Pot Sequential Pd-Catalyzed Suzuki−Miyaura Coupling and Cu-Catalyzed Amidation Reaction. Organic Letters (2010), 12 (6), 1352-1355. doi:10.1021/ol100300s.

[Gerardo-1] 1.0 ^1.1 ^1.2 Gerardo Cebrián-Torrejón, Nicolas Mackiewicz, Rafael P. Vázquez-Manrique, Alain Fournet, Bruno Figadère, Julien Nicolas, Erwan Poupon. Solution Phase and Nanoparticular Biosynthetically Inspired Interconnections in the Canthin-6-one β-Carboline Series and Study of Phenotypic Properties on C. elegans. European Journal of Organic Chemistry. 2013. 26. 5821-5828. doi:10.1002/ejoc.201300770.

[2] Gollner, Andreas; Koutentis, Panayiotis A. Two-Step Total Syntheses of Canthin-6-one Alkaloids: New One-Pot Sequential Pd-Catalyzed Suzuki−Miyaura Coupling and Cu-Catalyzed Amidation Reaction. Organic Letters (2010), 12 (6), 1352-1355. doi:10.1021/ol100300s.

[1]

[2]