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2-甲氧基-4-硝基苯胺

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2-甲氧基-4-硝基苯胺
别名 4-Nitro-o-anisidine, 4-Nitroanisidine
识别
CAS号 97-52-9
PubChem 7337
ChemSpider 7060
SMILES
 
  • COC1=C(C=CC(=C1)[N+](=O)[O-])N
性质
化学式 C7H8N2O3
摩尔质量 168.15 g·mol−1
外观 黄色固体
密度 1.42 g/cm3[1]
熔点 140-142 °C(271 K)
危险性
GHS危险性符号
《全球化学品统一分类和标签制度》(简称“GHS”)中有害物质的标签图案《全球化学品统一分类和标签制度》(简称“GHS”)中对人体有害物质的标签图案《全球化学品统一分类和标签制度》(简称“GHS”)中对环境有害物质的标签图案
GHS提示词 Warning
H-术语 H302, H351, H411
P-术语 P203, P261, P264, P264+265, P270, P271, P273, P280, P301+317, P302+352, P304+340, P305+351+338, P318, P319
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

2-甲氧基-4-硝基苯胺(英語:2-Methoxy-4-nitroaniline)是一种有机化合物,化学式O
2
NC
6
H
3
(OCH
3
)NH
2
,是甲氧基硝基苯胺的同分异构体之一[2],常温常压下为黄色固体,可用于合成颜料黄74[3],会影响几种细胞色素P450表达[4]

参考文献

[编辑]
  1. ^ Mehdi, S. Structure of 2-methoxy-4-nitroaniline. Acta Crystallographica Section C Crystal Structure Communications. 1992, 48 (4): 749–751. Bibcode:1992AcCrC..48..749M. doi:10.1107/S0108270191010739. 
  2. ^ Bao, Yuxin; Wu, Jiaxin; Zhao, Xi; Zhao, Hongkun. 2-Methoxy-4-nitroaniline Solubility in Several Monosolvents: Measurement, Correlation, and Solvent Effect Analysis. Journal of Chemical & Engineering Data. 2020, 65 (2): 757–765. doi:10.1021/acs.jced.9b00991. 
  3. ^ Penthala, Raju; Son, Young-A. Design, synthesis, and characterization of highly photostable Pigment Yellow 74 derivatives for painting applications. Dyes and Pigments. 2023-08, 216: 111358. doi:10.1016/j.dyepig.2023.111358. 
  4. ^ Degawa, Masakuni; Nakayama, Masafumi; Konno, Yoshihiro; Masubuchi, Kazuhiro; Yamazoe, Yasushi. 2-Methoxy-4-nitroaniline and its isomers induce cytochrome P4501A (CYP1A) enzymes with different selectivities in the rat liver. Biochimica et Biophysica Acta (BBA) - General Subjects. 1998, 1379 (3): 391–398. PMID 9545601. doi:10.1016/S0304-4165(97)00118-9.