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1,4-二氨基-5,8-二羟基蒽醌

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1,4-二氨基-5,8-二羟基蒽醌
识别
CAS号 16517-70-7  checkY
PubChem 85466
SMILES
 
  • C1=CC(=C2C(=C1N)C(=O)C3=C(C=CC(=C3C2=O)O)O)N
性质
化学式 C14H10N2O4
摩尔质量 270.24 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

1,4-二氨基-5,8-二羟基蒽醌是一种蒽醌有机化合物,化学式为C14H10N2O4,可作为酪蛋白激酶2(casein kinase 2,CK2)的抑制剂[1],可由分散紫1(1,4-二氨基蒽醌)和硫酸氯酸钠反应制得[2]

参考文献

[编辑]
  1. ^ De Moliner, E; Moro, S; Sarno, S; Zagotto, G; Zanotti, G; Pinna, LA; Battistutta, R. Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight.. The Journal of biological chemistry. 2003-01-17, 278 (3): 1831–6. PMID 12419810. doi:10.1074/jbc.M209367200. 
  2. ^ Pors, Klaus; Phillips, Roger M.; Patterson, Laurence H. Preparation of N-oxides of cytotoxic heterocyclylalkylaminoanthraquinones as hypoxia-targeting prodrugs in cancer treatment. 2006 WO2008062252 A1.