罗汉松脂酚
外观
罗汉松脂酚[1] | |
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IUPAC名 (8β,8′α)-4,4′-Dihydroxy-3,3′-dimethoxylignano-9,9′-lactone | |
系统名 (3R,4R)-3,4-Bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one | |
别名 | 罗汉松脂素、罗汉松脂醇、马台松脂醇 |
识别 | |
CAS号 | 580-72-3 |
PubChem | 119205 |
ChemSpider | 106491 |
SMILES |
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InChI |
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InChIKey | MATGKVZWFZHCLI-LSDHHAIUBP |
ChEBI | 6698 |
DrugBank | DB04200 |
KEGG | C10682 |
性质 | |
化学式 | C20H22O6 |
摩尔质量 | 358.39 g·mol−1 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
罗汉松脂酚(英语:Matairesinol),或译作罗汉松脂素、罗汉松脂醇、马台松脂醇等,是一种有机化合物。它被归类为木脂素,即苯丙素的一种。它存在于一些谷物中如黑麦,且和开环异落叶松树脂酚一样因其有益的营养作用而备受关注。[2]
代谢
[编辑]植物木脂素是肠木脂素(哺乳动物木脂素)的前体。[3]许多植物木脂素可代谢为肠木脂素(肠二醇和肠内酯),可降低某些癌症和心血管疾病的风险。[4]
生物医学考虑
[编辑]尽管一些研究认为木脂素具有预防疾病(保护心脏和激素相关癌症,如乳腺癌)的功效,但结果尚无定论。[5]罗汉松脂酚被发现可作为脂联素受体1的激动剂。[6]
参考资料
[编辑]- ^ Matairesinol (页面存档备份,存于互联网档案馆) at Sigma-Aldrich
- ^ Seibel, Wilfried; Kim Chung, Okkyung; Weipert, Dorian; Park, Seok-Ho, Cereals, Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH, 2005, doi:10.1002/14356007.a06_093.pub2
- ^ Niemeyer HB, Honig DM, Kulling SE, Metzler M. Studies on the metabolism of the plant lignans secoisolariciresinol and matairesinol. J. Agric. Food Chem. October 2003, 51 (21): 6317–25. PMID 14518962. doi:10.1021/jf030263n.
- ^ Milder IE, Arts IC, van de Putte B, Venema DP, Hollman PC. Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol. Br. J. Nutr. March 2005, 93 (3): 393–402. PMID 15877880. doi:10.1079/BJN20051371 .
- ^ Linus Pauling Institute at Oregon State University. [2023-10-18]. (原始内容存档于2015-04-08).
- ^ Sun Y, Zang Z, Zhong L, Wu M, Su Q, Gao X, Zan W, Lin D, Zhao Y, Zhang Z. Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay. PLOS ONE. 2013, 8 (5): e63354. Bibcode:2013PLoSO...863354S. PMC 3653934 . PMID 23691032. doi:10.1371/journal.pone.0063354 .