庚酸脱氢表雄酮

庚酸脱氢表雄酮
臨床資料
商品名（英语：Drug nomenclature）	With estradiol valerate: Gynodian Depot, others
其他名稱	DHEA enanthate; Prasterone heptanoate; DHEA heptanoate; DHEA-E; EDHEA; SH-90300-D; SH-70833-D (with EV); Androst-5-en-3β-ol-17-one 3β-heptanoate
给药途径	Intramuscular injection
藥物類別	Androgen; Anabolic steroid; Androgen ester; Estrogen; Neurosteroid
ATC碼	G03EA03 (WHO) ; A14AA07 (WHO);
法律規範狀態
法律規範	处方药（℞-only）;
藥物動力學數據
生物利用度	IM: 100%
代謝產物	• Prasterone (DHEA); • Others
生物半衰期	IM: 9 days; IV: 44 minutes
作用時間	18 days
排泄途徑	Urine, feces
识别信息
	IUPAC命名法 [(3S,8R,9S,10R,13S,14S)-10,13-Dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] heptanoate; ;
CAS号	23983-43-9
PubChem CID	163331;
DrugBank	DB16625;
ChemSpider	143333;
UNII	2W8I1S6T5L;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID00946833 ;
ECHA InfoCard	100.041.777
化学信息
化学式	C26H40O3
摩尔质量	400.60 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES CCCCCCC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CCC4=O)C)C;
	InChI InChI=1S/C26H40O3/c1-4-5-6-7-8-24(28)29-19-13-15-25(2)18(17-19)9-10-20-21-11-12-23(27)26(21,3)16-14-22(20)25/h9,19-22H,4-8,10-17H2,1-3H3/t19-,20-,21-,22-,25-,26-/m0/s1; Key:HHENOUDBWKNPAB-BNCSLUSBSA-N;

庚酸脱氢表雄酮（英語：Prasterone enanthate，或dehydroepiandrosterone enanthate，缩写DHEA-E，商品名有Gynodian Depot等）是一种有机化合物，化学式C
26H
40O
3，为脱氢表雄酮的庚酸酯，属于雄激素酯药物。^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]

参考文献

^ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Gynodian® Depot. Bayer (Schweiz) AG. compendium.ch. 16 October 2017 [15 January 2022]. （原始内容存档于29 May 2019）.
^ Modern Medicine (PDF). [2019-01-08]. （原始内容 (PDF)存档于2019-01-09）.
^ Gynodian Depoty (PDF). www.sukl.cz. [15 January 2022]. （原始内容 (PDF)存档于29 May 2019）.
^ Horsky J, Presl J. Ovarian Function and its Disorders: Diagnosis and Therapy. Springer Science & Business Media. 6 December 2012: 146–. ISBN 978-94-009-8195-9.
^ Platt D. Geriatrics 3: Gynecology · Orthopaedics · Anesthesiology · Surgery · Otorhinolaryngology · Ophthalmology · Dermatology. Springer Science & Business Media. 6 December 2012: 6–. ISBN 978-3-642-68976-5.
^ Campbell S. The Management of the Menopause & Post-Menopausal Years: The Proceedings of the International Symposium held in London 24–26 November 1975 Arranged by the Institute of Obstetrics and Gynaecology, The University of London. Springer Science & Business Media. 6 December 2012: 395–. ISBN 978-94-011-6165-7.
^ Bagatell C, Bremner WJ. Androgens in Health and Disease. Springer Science & Business Media. 27 May 2003: 277–. ISBN 978-1-59259-388-0.
^ Frigo P, Eppel W, Asseryanis E, Sator M, Golaszewski T, Gruber D, et al. The effects of hormone substitution in depot form on the uterus in a group of 50 perimenopausal women--a vaginosonographic study. Maturitas. April 1995, 21 (3): 221–225. PMID 7616871. doi:10.1016/0378-5122(94)00893-c.