描述Writing by a Parkinson's disease patient.png	English: Writing by a patient with Parkinson's disease, showing abnormalities, which may include micrographia
日期	1879年
来源	Lectures on the diseases of the nervous system. Published 1879. Second edition by H. C. Lea in Philadelphia. Lecture V: On paralysis agitans. (p. 112)
作者	Jean-Martin Charcot
授权 (二次使用本文件)	Public domainPublic domainfalsefalse 本作品在其来源国以及其他著作权期限是作者逝世后100年或以下的国家和地区属于公有领域。 你必须增加美国公有领域标签显示为何这个作品在美国属于公有领域。 本文件已被确认为免除已知的著作权法限制（包括所有相关权利）。 https://creativecommons.org/publicdomain/mark/1.0/PDMCreative Commons Public Domain Mark 1.0falsefalse
其他版本	File:Writing by a Parkinson's disease patient.jpg

Text accompanying the image in the original source:

The tremor causes the handwriting to exhibit characters which are somewhat special. When the disease is commencing, the writing at first glance seems normal, but when examined with a magnifying glass inequalities are perceived, some parts being thicker and heavier than others. Later on, in the period of stationary intensity for instance, the changes are more marked and consequently plainer. The specimen, Fig. 7 (p. 112), represents the writing of a patient whose case we studied at the Hôpital St. Louis, in 1869. The strokes forming the letters are very irregular and sinuous, whilst the irregularities and sinuosities are of a very limited width (Bourneville).
On a careful examination of this specimen of writing it will be perceived that the down-strokes are all, with the exception of the first letter, made with comparative firmness and are, in fact, nearly normal — the finer up-strokes, on the contrary, are all tremulous in appearance, and it is to the unsteadiness of these lines that the peculiar character of the writing here is principally due. From this I would infer, that the flexors of the fingers were, at this stage of the disease, less affected by tremor than the extensors, and that, amongst the latter, the interossei were probably the earliest affected. This inference will not be without interest for those who remember the attention which Dr. Duchenne (de Boulogne) gave to the conduct of these muscles in the various paralytic and atrophic affections of the hand (Sigerson).

The handwritten text reads: "Catherine Metzger 13 Octobre 1869".